Beta Glucan and Prozyme Nutrition Product Line

Beta Glucan - Pro-zyme - Equine Solutions Catalog Page 22b

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Beta Glucan

Active Forms: Beta-1, 3-D glucan with 1,6 glucan side chains, which are derived from yeast,
and other fungal forms, including varieties of mushrooms. There are also glucans that occur in grains,
such as oats and barley that are composed of a 1, 4-linked glucose molecule.

Beta Glucan - Beta-1,3-D glucan

Beta glucan is a scientifically proven biological defense modifier (BDM)
that nutritionally potentiates and modulates the immune response primarily
through macrophage and dendritic immune cells to safely yield various therapeutic effects.
For many years Glucans have been investigated for these immune enhancing properties,
particularly their ability to activate macrophage immune cells and, in turn,
the T-Cells, NK-Cells and B-Cells including selected cytokines and complement.
A Macrophage

An activated macrophage resembles an angry octopus extending tentacle-like arms,
physically pulling in infectious invaders and ingesting and destroying them with caustic enzymes.

Beta Glucan is a powerful immune stimulator, activating the macrophage in the immune system.
Studies have found this product not only has a positive action on the macrophage, but
on B lymphocytes, (NK) natural killer cells and suppressor T cells. In addition to these important
functions, Beta Glucan is an effective antioxidant and free radical scavenger. Beta Glucan
is a safe, non-toxic, and orally effective supplement for those who wish to enhance their
immune system and lower cholesterol levels. The use of beta glucan will build an immune
system capable of killing the flu virus and/or shortening the duration of any flu symptoms.
Beta Glucan can come in a yeast or mushroom base.

-- Maximum stimulation of the macrophage with Beta 1,3,1/6 Glucan
-- The body's ultimate self-defense mechanism
Starting in the 1940's, researchers have investigated the nutritional benefits of Beta Glucan.
Derived from broken cell walls of yeast, mushrooms, barley and oats, Beta Glucans are capable
of reducing unhealthy amounts of serum cholesterol and boosting the immune system.

Beta Glucan is the only glucan found effective in preventing coronary heart disease by SIGNIFICANTLY
lowering LDL blood cholesterol and increasing HDL (good) cholesterol levels.
Read the U.S. Food and Drug Administration's official announcement at
FDA APPROVES BETA GLUCAN FOR PREVENTING CORONARY HEART DISEASE.

Quaker Oats, the cereal manufacturer, has a wonderful website clearly explaining how the abundant
beta glucan in oatmeal provides remarkable cholesterol lowering power. Please remember you would
have to eat 32 bowls of Quaker Oats to get the same amount of beta glucan you get in one of our 200 mg tablets.

WHAT IS BETA GLUCAN AND WHY IS IT IMPORTANT?
A NATURAL, NON-TOXIC, NON-SPECIFIC IMMUNE RESPONSE ENHANCER Glucans are sugar
molecules found in every living thing from a blade of grass to an elephant. There are many different types
found to date. Fueled by research in immunology and cancer over the past 50 years, there is much interest
in Beta Glucans. Beta 1,3 Glucan is a very specific polyglucose molecule which research has proven. More
specifically, in its natural combination with Beta 1,6, Glucan activates non-specific immune response
cascades via macrophages, monocytes, neutrophitis, etc., as well as enhances the function of natural killer cells (NK)
and other immune factors such as interferon, tumor necroses factors, and interlukins-1,2 and 6.
Non-specific means it is very broad in the action it provokes, stimulating an immune cascade for cells
to be able to recognize and to go after any foreigner, whether cancer cells, yeast, virus, proteins from
undigested foods, pollens and pet dander, cellular debris, etc.

Research references are available by the hundreds, dating back to the 1940's. Recent research efforts are
ongoing [Harvard, Baylor, Univ. of Oregon, Georgia, Michigan, Texas and others], and the more we discover
about substances such as aloe, miatake mushrooms, lentinen, reishi mushrooms, chitosan, and many other
substances that seem to have definite immune modulating effects, we discover that one of the main common
factors in these other extracts is a Beta 1,3 Glucan linkage. This molecule is the key that fits into the receptor
on the macrophage and stimulates the cell to start the cascade.

read more below....In the Beginning....

Beta Glucan/ Colostrum Blend 1- lb $65.00
Price may vary from shipment to shipment.

Price may vary from shipment to shipment.

COLOSTRUM
(see COLOSTRUM article)

"Natural Alternative to Protect the Immune Function of Your Horse"

Boosts Under Active Immune System

Enhances Energy & Stamina

Lowers Risk of Health Problems Related to Stress & Travel

Colostrum contains over 37 different important natural immune factors and more than 8 growth factors that work to combat illness and promote health while providing maximum benefits.

There have been over 20,000 scientific studies and research articles performed on colostrum and more health benefits are being discovered every day. Studies have factors (Immunoglobulins, Lactoferrin, Leukocytes, Cytokines and Interferon) that help restore immune function to normal and help protect against infection while the growth factors work to repair and reverse the damage caused by age, disease, stress and injuries.

*** Colostrum is the safe alternative to antibiotics with no side effects ***

immune factors help support and regulate the immune system while its growth factors help regenerate
cellular tissue, regulate glucose, build lean muscle mass, target fat for energy and increases endurance

Item Colostrum 12oz $29.99

Item Colostrum 3# (48 oz.) $130.00

Item Colostrum 6# (96 oz.) $230.00

Item Colostrum 120 caps $30.00

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Beta Glucan Caps Beta-1,3-D glucan (80+% purity - highest available on the market)
120 (120 mg) v-caps
(most of the market out there offers as low as 14% - ask obout purity level)
Price may vary from shipment to shipment.

Used for and to prevent bacterial, anti-biotic resistant fungal and viral infections
General immune enhancement
Speeds up healing of exercise induced injuries
Lowers cholesterol naturally
Speeds wound and surgery healing naturally
Helps in fighting infectious diseases, cancer (breast, colon, prostate),
aides immune system during radiation treatments (cancer therapy)

» 100 V caps $31.95
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Beta Glucan Powder Beta-1,3-D glucan (85+% purity - highest available on the market)
(most of the market out there offers as low as 14% - ask obout purity level)
Price may vary from shipment to shipment.

Higher potency
Excellent for animals who suffer with chronic degenerative diseases
Especially effective in animals who have had poor nutrition,
or with compromised immune systems

Used for and to prevent bacterial, anti-biotic resistant fungal and viral infections
General immune enhancement
Speeds up healing of exercise induced injuries
Lowers cholesterol naturally
Speeds wound and surgery healing naturally
Helps in fighting infectious diseases, cancer (breast, colon, prostate),
aides immune system during radiation treatments (cancer therapy)

» 8 oz. $50.00
» 1 lbs. $65.00
» 1 KILO $110.00

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Beta Glucan/ Colostrum Blend 1- lb $65
Price may vary from shipment to shipment. Beta Glucan prices are volitile.

Price may vary from shipment to shipment.

Beta Glucan - Animal Feed Grade powder Beta-1,3-D glucan (30% purity)
NO LONGER AVAILABLE
(most of the market out there offers as low as 14% - ask obout purity level)

Beta Glucan is a safe and very potent nutritional supplement
Beta Glucan has been given a GRAS (Generally Recognized As Safe) rating by the FDA.
Feed Beta Glucan to heighten immune response & defenses
Stimulate the immune system in general
Speeds up wound healing
30% is the normal grade of Beta Glucan for animal use

» 8 oz. $25.00
» 1 lbs. $40.00
» 5 lbs. $200.00

In the Beginning...

Since the 1940s, scientists, through Beta Glucan Research, have been evolving the scientific
evidence of the remarkable abilities of a simple substance derived from baker's yeast
to effectively potentiate and activate the immune response, and to work through
nutritional potentiation of the immune response in the body's war against cancer,
ulcers, radiation exposure, infection, and trauma.

The story of beta glucan begins with the study of Zymosan, a drug used throughout Europe.
Zymosan, an immune stimulator, is composed of a crude mixture of yeast cell wall
materials including proteins, lipids, and polysaccharides synthesized into a drug,
which unfortunately has many negative side effects in patients.

Louis Pillemer, Ph.D., and his colleagues first studied the drug Zymosan in the 1940s
and discovered Zymosan was able to nonspecifically potentiate and modulate the immune system.
Zymosan activated the immune response regardless of the type of invader or pathogen,
including viruses, bacteria, fungi, parasite and tumors.

The Dr. DiLuzio' Breakthrough
In the 1960s, Nicholas DiLuzio, Ph.D., conducted additional research at Tulane University
discovering the active immune-activating compound within the drug component of Zymosan
was Beta-1, 3-D-glucan, a long-chained polysaccharide absent the negatives of Zymosan with
to date no known toxicity or side effects. Since that critical break through by Dr. DiLuzio,
scientists have determined how beta glucan works to activate the macrophage immune cells
and in turn the entire immune response. Dr. D.L. Williams and Dr. I.W. Browder worked
with Dr. DiLuzio in much of this research and contributed both then and still today in
the growing body of Beta glucan research.

Beta-1,3-glucan's beneficial role in treating cancer was illuminated in 1975 by Peter W. Mansell, M.D.,
and colleagues, as reported in the Journal of the National Cancer Institute.
Nodules of malignant skin cancer in nine patients were injected with beta-1,3-glucan.
The size of the cancer lesions was "strikingly reduced in as short a
period as five days" and in small lesions "resolution was complete," Dr. Mansell reported.

This product is important for helping keep host resistance and detoxification mechanisms at optimal levels.
Individuals with compromised immune systems can benefit greatly as well as being beneficial with occasional
use by those just wishing to improve their resistance and offset the daily toll stress takes. Great for anyone,
but especially families with small children, pets, livestock, etc. A MUST for cancer patients undergoing chemo and radiation therapy.

Mediates destruction of malignant cells [Journal of National Cancer Institute, 54, No. 3:571, 1975]
Inhibits tumor growth and enhances survival rates [Adv. Exp. Med. Biol., 121A, 259-290, 1980]

Stimulates tumor cell destruction [Scand. J. Immunol. 15:297-304; Diss. Abst. Int. Sci. 48:1263, 1987]

Free radical scavenger par excellence [currently used in high-end skin care lines such as Elizabeth Arden]

Increases longevity for cancer patients after chemo with fewer side effects and less recurrence.

Improves host resistance to infections of all sorts [Trends in Pharm. Sciences 4:33; 344-347, 1983]

Virucidal, fungicidal, bactericidal. Protects against post-surgical cepsis [Scand J. Gastroent. 23:261-267, 1987]

Anti-allergenic, anti-rheumatic [Scand. J. Rheumatology 76:67-72, 1988] Stops and reverses damage from radiation [Radiation Research 117:59-69, 1989; USAF Radiobiology Inst., Bethesda MD, 1989]

Peritoneal macrophages doubled their activity in mice fed oral B13G, proving systemic effects via oral administration on par with injectable [Baylor College of Medicine, Research Report, 1988]

Patients survival rates increased as a result of using Beta Glucans [Todd, R.F., J of Clinical Invest. Vol 98, 1-2. 1996; Div of Hematology/Oncology Dept of Int. Med., Univ. of MI Med Center]

Enhances antibiotic efficacy in rats infected with antibiotic-resistant bacteria [Ann. of NY Acad. Sci. 797:285-284, Oct 1996]

Interesting Beta Glucan, The Immune System and Cancer info

http://www.betaglucan.org/history.htm

http://www.betaglucan.org/ Here is some Beta Glucan Research to read.

These statements have not been evaluated by the FDA (USA).
This product is not intended to diagnose, treat, cure, or prevent any disease.
You should carefully read all product packaging and labels. If you have
or suspect that you have a medical problem, promptly contact your medical professional.

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